# STOCKHOLM 1.0 #=GF ID 14-3-3 #=GF AC PF00244 #=GF DE 14-3-3 protein #=GF AU Finn RD #=GF AL Clustalw #=GF SE Prosite #=GF GA 25 25 #=GF TC 35.40 35.40 #=GF NC 19.10 19.10 #=GF TP Domain #=GF BM hmmbuild -f HMM SEED #=GF BM hmmcalibrate --seed 0 HMM #=GF RN [1] #=GF RM 95327195 #=GF RT Structure of a 14-3-3 protein and implications for #=GF RT coordination of multiple signalling pathways. #=GF RA Xiao B, Smerdon SJ, Jones DH, Dodson GG, Soneji Y, Aitken #=GF RA A, Gamblin SJ; #=GF RL Nature 1995;376:188-191. #=GF RN [2] #=GF RM 95327196 #=GF RT Crystal structure of the zeta isoform of the 14-3-3 #=GF RT protein. #=GF RA Liu D, Bienkowska J, Petosa C, Collier RJ, Fu H, Liddington #=GF RA R; #=GF RL Nature 1995;376:191-194. #=GF RN [3] #=GF RM 96182649 #=GF RT Interaction of 14-3-3 with signaling proteins is mediated #=GF RT by the recognition of phosphoserine. #=GF RA Muslin AJ, Tanner JW, Allen PM, Shaw AS; #=GF RL Cell 1996;84:889-897. #=GF RN [4] #=GF RM 97424374 #=GF RT The 14-3-3 protein binds its target proteins with a common #=GF RT site located towards the C-terminus. #=GF RA Ichimura T, Ito M, Itagaki C, Takahashi M, Horigome T, #=GF RA Omata S, Ohno S, Isobe T #=GF RL FEBS Lett 1997;413:273-276. #=GF RN [5] #=GF RM 96394689 #=GF RT Molecular evolution of the 14-3-3 protein family. #=GF RA Wang W, Shakes DC #=GF RL J Mol Evol 1996;43:384-398. #=GF RN [6] #=GF RM 96300316 #=GF RT Function of 14-3-3 proteins. #=GF RA Jin DY, Lyu MS, Kozak CA, Jeang KT #=GF RL Nature 1996;382:308-308. #=GF DR PROSITE; PDOC00633; #=GF DR SMART; 14_3_3; #=GF DR PRINTS; PR00305; #=GF DR SCOP; 1a4o; fa; #=GF DR INTERPRO; IPR000308; #=GF DR PDB; 1a37 A; 3; 228; #=GF DR PDB; 1a37 B; 3; 228; #=GF DR PDB; 1a38 A; 3; 228; #=GF DR PDB; 1a38 B; 3; 228; #=GF DR PDB; 1a4o A; 3; 228; #=GF DR PDB; 1a4o B; 3; 228; #=GF DR PDB; 1a4o C; 3; 228; #=GF DR PDB; 1a4o D; 3; 228; #=GF DR PDB; 1qja B; 3; 229; #=GF DR PDB; 1qja A; 3; 230; #=GF DR PDB; 1qjb A; 3; 232; #=GF DR PDB; 1qjb B; 3; 232; #=GF SQ 148 #=GS O61131/11-251 AC O61131 #=GS 143L_ARATH/7-245 AC P48349 #=GS O49082/8-245 AC O49082 #=GS 143R_ARATH/7-245 AC P42647 #=GS 1433_XENLA/1-227 AC P29309 #=GS 1433_ENTHI/1-236 AC P42650 #=GS Q24902/13-244 AC Q24902 #=GS 1432_ENTHI/4-238 AC P42649 #=GS O24222/3-240 AC O24222 #=GS 143Z_SHEEP/3-236 AC P29361 #=GS 1433_CANAL/5-240 AC O42766 #=GS 143X_MAIZE/1-56 AC P29306 #=GS 143B_BOVIN/4-237 AC P29358 #=GS Q42106/1-38 AC Q42106 #=GS Q9VEA8/4-239 AC Q9VEA8 #=GS O96436/9-256 AC O96436 #=GS P93787/9-246 AC P93787 #=GS 1435_LYCES/5-242 AC P93210 #=GS 1434_LYCES/6-243 AC P42652 #=GS 1431_LYCES/9-246 AC P93206 #=GS Q9XEW6/1-118 AC Q9XEW6 #=GS 1433_LYCES/9-246 AC P93209 #=GS 143E_DROME/4-239 AC P92177 #=GS 143G_BOVIN/3-240 AC P29359 #=GS 1433_TOBAC/5-239 AC Q41246 #=GS Q9UR29/5-240 AC Q9UR29 #=GS Q9UP48/1-164 AC Q9UP48 #=GS Q9SP07/8-245 AC Q9SP07 #=GS Q42260/1-75 AC Q42260 #=GS 143G_RAT/3-240 AC P35214 #=GS Q9XEW7/1-93 AC Q9XEW7 #=GS 1432_MAIZE/8-245 AC Q01526 #=GS 1433_TRIHA/3-238 AC Q99002 #=GS Q9XYW8/1-233 AC Q9XYW8 #=GS Q9S9Z8/5-240 AC Q9S9Z8 #=GS 1431_SCHMA/14-246 AC Q26540 #=GS Q21539/1-97 AC Q21539 #=GS 1438_LYCES/7-131 AC P93213 #=GS Q9T0N0/8-245 AC Q9T0N0 #=GS O24221/9-246 AC O24221 #=GS 143B_HUMAN/4-237 AC P31946 #=GS O24223/8-249 AC O24223 #=GS O70456/3-238 AC O70456 #=GS O80367/7-242 AC O80367 #=GS Q9SEC9/1-127 AC Q9SEC9 #=GS O77642/3-238 AC O77642 #=GS Q28541/1-40 AC Q28541 #=GS 1433_ORYSA/8-245 AC Q06967 #=GS Q9XG89/8-245 AC Q9XG89 #=GS 143A_TOBAC/5-241 AC P93342 #=GS 1433_SOLTU/5-242 AC Q41418 #=GS 143B_RAT/4-237 AC P35213 #=GS 1435_SOLTU/5-243 AC P93784 #=GS Q39558/8-246 AC Q39558 #=GS 143S_HUMAN/3-238 AC P31947 #=GS O61132/1-232 AC O61132 #=GS 143B_SOYBN/6-244 AC Q96451 #=GS 143C_SOYBN/7-242 AC Q96452 #=GS 1433_MESCR/7-244 AC P93259 #=GS 1433_CAEEL/5-237 AC P41932 #=GS O76466/1-54 AC O76466 #=GS BMH1_YEAST/4-240 AC P29311 #=GS 143E_ARATH/5-240 AC P48347 #=GS Q9SCA7/1-230 AC Q9SCA7 #=GS Q06854/1-144 AC Q06854 #=GS 143T_MOUSE/3-236 AC P35216 #=GS 143P_ARATH/4-241 AC P42644 #=GS 143O_ARATH/5-242 AC Q01525 #=GS 143M_ARATH/7-242 AC Q96299 #=GS 143K_ARATH/7-245 AC P48348 #=GS 143Z_MOUSE/3-236 AC P35215 #=GS 143U_ARATH/7-244 AC P42645 #=GS 143F_MOUSE/3-240 AC P11576 #=GS 143H_ARATH/11-248 AC P46077 #=GS 143B_VICFA/7-242 AC P42654 #=GS 1431_ENTHI/4-239 AC P42648 #=GS 143A_VICFA/8-245 AC P42653 #=GS 1433_OENHO/8-245 AC P29307 #=GS 143A_LYCES/11-138 AC P93207 #=GS 1433_DICDI/3-238 AC P54632 #=GS O24001/9-246 AC O24001 #=GS 1432_SCHMA/1-205 AC Q26537 #=GS Q42058/7-112 AC Q42058 #=GS Q9SHV6/16-54 AC Q9SHV6 #=GS 1433_CHLRE/5-242 AC P52908 #=GS O70455/5-238 AC O70455 #=GS Q9XEW4/21-220 AC Q9XEW4 #=GS O60955/9-251 AC O60955 #=GS P93785/3-240 AC P93785 #=GS O65165/1-21 AC O65165 #=GS Q9UAH0/5-239 AC Q9UAH0 #=GS O57468/4-239 AC O57468 #=GS O96945/8-241 AC O96945 #=GS Q9U491/4-239 AC Q9U491 #=GS 1432_LYCES/3-240 AC P93208 #=GS Q42053/5-100 AC Q42053 #=GS O81976/1-54 AC O81976 #=GS Q9U408/13-244 AC Q9U408 #=GS 1436_LYCES/5-243 AC P93211 #=GS 1437_LYCES/5-129 AC P93212 #=GS Q9XEW5/1-219 AC Q9XEW5 #=GS Q9V5G6/6-144 AC Q9V5G6 #=GS O61173/2-194 AC O61173 #=GS O70457/4-241 AC O70457 #=GS Q42020/1-90 AC Q42020 #=GS 1433_SPIOL/1-198 AC P29308 #=GS Q42083/11-79 AC Q42083 #=GS Q9SFK4/1-214 AC Q9SFK4 #=GS 1431_MAIZE/8-245 AC P49106 #=GS Q9XEW3/1-100 AC Q9XEW3 #=GS Q9XEW8/1-86 AC Q9XEW8 #=GS 143Z_XENLA/3-238 AC Q91896 #=GS Q9U8K4/15-247 AC Q9U8K4 #=GS 1439_LYCES/7-131 AC P93214 #=GS 143Z_DROME/6-239 AC P29310 #=GS O49152/7-242 AC O49152 #=GS 1433_HELAN/8-246 AC O65352 #=GS 143E_HUMAN/4-239 AC P42655 #=GS 143G_HUMAN/4-238 AC Q9UN99 #=GS 143C_ARATH/10-247 AC P42643 #=GS Q9UDP2/1-212 AC Q9UDP2 #=GS 143B_TOBAC/3-241 AC O49995 #=GS O57469/3-236 AC O57469 #=GS Q9SWP7/7-245 AC Q9SWP7 #=GS Q9XZV0/2-235 AC Q9XZV0 #=GS 1434_SOLTU/5-241 AC Q43643 #=GS 143A_SOYBN/6-243 AC Q96450 #=GS 143T_HUMAN/3-236 AC P27348 #=GS 1433_FUCVE/4-237 AC Q39757 #=GS 1433_PEA/8-245 AC P46266 #=GS 143F_TOBAC/5-243 AC O49998 #=GS 143E_TOBAC/6-243 AC O49997 #=GS P93786/8-245 AC P93786 #=GS 143D_SOYBN/7-242 AC Q96453 #=GS 143C_TOBAC/8-245 AC P93343 #=GS 1434_CAEEL/5-238 AC Q20655 #=GS 143Z_HUMAN/3-236 AC P29312 #=GS BMH2_YEAST/4-240 AC P34730 #=GS 143D_TOBAC/9-246 AC O49996 #=GS Q9XYW7/4-229 AC Q9XYW7 #=GS O24533/1-181 AC O24533 #=GS 143F_HUMAN/3-240 AC Q04917 #=GS 143A_HORVU/8-245 AC P29305 #=GS RA25_SCHPO/5-240 AC P42657 #=GS 1433_NEOCA/9-251 AC Q25538 #=GS RA24_SCHPO/6-241 AC P42656 #=GS 143B_HORVU/9-246 AC Q43470 #=GS 143N_ARATH/5-242 AC Q96300 #=GS 143Z_HUMAN/3-236 DR PDB; 1a37 A; 3; 228; #=GS 143Z_HUMAN/3-236 DR PDB; 1a37 B; 3; 228; #=GS 143Z_HUMAN/3-236 DR PDB; 1a38 A; 3; 228; #=GS 143Z_HUMAN/3-236 DR PDB; 1a38 B; 3; 228; #=GS 143Z_HUMAN/3-236 DR PDB; 1a4o A; 3; 228; #=GS 143Z_HUMAN/3-236 DR PDB; 1a4o B; 3; 228; #=GS 143Z_HUMAN/3-236 DR PDB; 1a4o C; 3; 228; #=GS 143Z_HUMAN/3-236 DR PDB; 1a4o D; 3; 228; #=GS 143Z_HUMAN/3-236 DR PDB; 1qja B; 3; 229; #=GS 143Z_HUMAN/3-236 DR PDB; 1qja A; 3; 230; #=GS 143Z_HUMAN/3-236 DR PDB; 1qjb A; 3; 232; #=GS 143Z_HUMAN/3-236 DR PDB; 1qjb B; 3; 232; O61131/11-251 RSDCTYRSKLAEQAERYDEMADAMRTLVEQCVnn.......dkdELTVEERNLLSVAYKNAVGARRASWRIISSVEQKEMSKA.NVHNKNIAATYRKKVEEELNNIC.QDILN.LLTKKLIPNT..SESESKVFYYKMKGDYYRYISEFS.CDE.GKKEASNFAQEAYQKATDIAENELPSTHPIRLGLALNYSVFFY..EILNQPHQACEMAKRAF...DDAITEFDNV..SEDS..YKDSTLI.MQLLRDNLTLWTSDLQGDQ O61132/1-232 ---------LAEQAERYDEMADAMRTLVEQCVnn.......dkdELTVEERNLLSVAYKNAVGARRASWRIISSVEQKEMSKA.NVHNKNVAATYRKKVEEELNNIC.QDILN.LLTKKLIPNT..SESESKVFYYKMKGDYYRYISEFS.CDE.GKKEASNFAQEAYQKDTDIAENELPSTHPIRLGLALNYSVFFY..EILNQLHQACEMAKRAF...DDAITEFDNV..SEDS..YKDSTLI.MQLLRDNLTLWTSDLQGDQ O96436/9-256 REEHVYRAKLAEQAERYDEMAEAMKNLVENCLdqnnsppgakgdELTVEERNLLSVAYKNAVGARRASWRIISSVEQKEANRN.HMANKALAASYRQKVENELNKIC.QEILT.LLTDKLLPRT..TDSESRVFYFKMKGDYYRYISEFS.NEE.GKKASAEQAEESYKRATDTAEAELPSTHPIRLGLALNYSVFYY..EILNQPQKACEMAKLAF...DDAITEFDSV..SEDS..YKDSTLI.MQLLRDNLTLWTSDLQTQE O60955/9-251 RDEYVYKAKLAEQAERYDEMAEAMKNLVENCLdeq.....qpkdELSVEERNLLSVAYKNAVGARRASWRIISSVEQKELSKQ.HMQNKALAAEYRQKVEEELNKIC.HDILQ.LLTDKLIPKT..SDSESKVFYYKMKGDYYRYISEFS.GEE.GKKQAADQAQESYQKATETAEAELPSTHPIRLGLALNYSVFFY..EILNLPQQACEMAKRAF...DDAITEFDNV..SEDS..YKDSTLI.MQLLRDNLTLWTSDLQADQ 1433_NEOCA/9-251 RDEYVYKAKLAEQAERYDEMAEAMKNLVENCLdeq.....qpkdELSVEERNLLSVAYKNAVGARRASWRIISSVEQKELSKQ.HMQNKALAAEYRQKVEEELNKIC.HDILQ.LLTDKLIPKT..SDSESKVFYYKMKGDYYRYISEFS.GEE.GKKQAADQAQESYQKATETAEGHSPATHPIRLGLALNYSVFFY..EILNLPQQACEMAKRAF...DDAITEFDNV..SEDS..YKDSTLI.MQLLRDNLTLWTSDLQADQ Q21539/1-97 --------------------------------............---------------------------------------.-----------------------.-----.----------..-----------MVADHFRYLVQYD.-DI.NREEHAHKSRIAYQEALGIAKDKMQPTHPIRLGLALNASALNF..DVLNLPKEANEIAQSAL...DSAHRELEKMksSLDS..YDISNL-.------------------- O65165/1-21 --------------------------------............---------------------------------------.-----------------------.-----.----------..------------------------.---.-------------------------------------------..-----------------...----------..----..-----LI.MQLLRDNLTLWTSDMQEDG Q9U491/4-239 REALVYRAKLAEQLERYDEMVDAMKEVVEMAE............ELTVEERNLLSVAYKNVIGSRRSSWRVFSAVEQTEGNRG.NAEKQACAKKFREVLESELDRVS.KDILE.LIDKYLIKSA..TKSDSKVFYLKMKGDYFRYMAEFS.VDP.QRKKAAEESNKAYQEASEIAATQLFPTHPIRLGLALNYSVYFY..EIMNDPDEACRLAQAAF...DDAIAKLDQL..SEES..YKDSTLI.MQLLRDNLTLWTSDPERDD 1433_XENLA/1-227 -------AKLSEQAERYDDMAASMKAVTELGA............ELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEG--.NDKRQQMAREYREKVETELQDIC.KDVLD.LLDRFLVPNA..TPPESKVFYLKMKGDYYRYLSEVA.SGD.SKQETVASSQQAYQEAFEISKSEMQPTHPIRLGLALNFSVFYY..EILNSPEKACSLAKSAF...DEAIRELDTL..NEES..YKDSTLI.MQLLRDNLTLWTSENQGEE 143B_BOVIN/4-237 KSELVQKAKLAEQAERYDDMAAAMKAVTEQGH............ELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTER--.NEKKQQMGKEYREKIEAELQDIC.NDVLQ.LLDKYLIPNA..TQPESKVFYLKMKGDYFRYLSEVA.SGD.NKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYY..EILNSPEKACSLAKTAF...DEAIAELDTL..NEES..YKDSTLI.MQLLRDNLTLWTSENQGDE 143B_HUMAN/4-237 KSELVQKAKLAEQAERYDDMAAAMKAVTEQGH............ELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTER--.NEKKQQMGKEYREKIEAELQDIC.NDVLE.LLDKYLIPNA..TQPESKVFYLKMKGDYFRYLSEVA.SGD.NKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYY..EILNSPEKACSLAKTAF...DEAIAELDTL..NEES..YKDSTLI.MQLLRDNLTLWTSENQGDE 143B_RAT/4-237 KSELVQKAKLAEQAERYDDMAAAMKAVTEQGH............ELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTER--.NEKKQQMGKEYREKIEAELQDIC.SDVLE.LLDKYLILNA..THAESKVFYLKMKGDYFRYLSEVA.SGD.NKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYY..EILNSPEKACSLAKTAF...DEAIAELDTL..NEES..YKDSTLI.MQLLRDNLTLWTSENQGDE O70455/5-238 KSELVHKAKLAEQAERYDDMAAAMKAVTEQGH............ELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTER--.DEKKQQMGKEYREKIEAELQDIC.NDVLE.LLDKYLILNA..TQAESKVFYLKMKGDYFRYLSEVA.SGE.NKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYY..EILNSPEKACSLAKTAF...DEAIAELDTL..NEES..YKDSTLI.MQLLRDNLTLWTSENQGDE 143Z_SHEEP/3-236 KNELVQKAKLAEQAERYDDMAACMKSVTEQGA............ELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEG--.AEKKQQMAREYREKIETELRDIC.NDVLS.LLEKFLIPNR..SQPESKVFYLKMKGDYYRYLAEVA.AGD.DKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYY..EILNSPEKACSLAKTAF...DEAIAELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDTQGDE 143Z_MOUSE/3-236 KNELVQKAKLAEQAERYDDMAACMKSVTEQGA............ELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEG--.AEKKQQMAREYREKIETELRDIC.NDVLS.LLEKFLIPNA..SQPESKVFYLKMKGDYYRYLAEVA.AGD.DKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYY..EILNSPEKACSLAKTAF...DEAIAELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDTQGDE 143Z_HUMAN/3-236 KNELVQKAKLAEQAERYDDMAACMKSVTEQGA............ELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEG--.AEKKQQMAREYREKIETELRDIC.NDVLS.LLEKFLIPNA..SQAESKVFYLKMKGDYYRYLAEVA.AGD.DKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYY..EILNSPEKACSLAKTAF...DEAIAELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDTQGDE #=GR 143Z_HUMAN/3-236 SS HHHHHHHHHHHHHTTCHHHHHHHHHHHHTTSC............CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTT--.CCHHHHHHHHHHHHHHHHHHHHH.HHHHH.HHHHTTTTCC..CSCHHHHHHHHHHHHHHHHHHHHC.CSC.HHHHHHHHHHHHHHHHHHHHHCHCCTTCHCHHHHHHHHHHHHC..HTSCCHHHCHHHHHHHH...HHHHTTCGGC..CTTT..HHHHHHH.HHHHHHHHHHCTCCCXXXX #=GR 143Z_HUMAN/3-236 SA 26310320300350512510050022003352............4045500400120033002310402420152179179--.38752510440144014203510.43002.0035201642..754403000010100011100201.867.7465125302500340252067635113122100001001127..31372485135106412...5415867932..3994..6651462.142043126627759XXXX 143Z_XENLA/3-238 KNELVQKAKLAEQAERYDDMAACMKRVTEEGG............ELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEG--.AEKKQEMSREYREKIEAELREIC.NDVLN.LLDKFLIANA..TQPESKVFYLKMKGDYYRYLAEVA.AGN.AKTEIVGQSQKAYQDAFDISKTEMQPTHPIRLGLALKLLCVLTneESSTVQDKACALAKAAF...DEAIAELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDTQGDE O57469/3-236 KNELVQKAKLAEQAERYDDMAACMKRVTEEGG............ELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEG--.AEKKQEMSREYREKIEAELREIC.NDVLN.LLDKFLIANA..TQPESKVFYLKMKGDYYRYLAEVA.AGN.AKTEIVGQSQKAYQDAFDISKTEMQPTHPIRLGLALNFSVFYY..EILNCPDKACALAKAAF...DEAIAELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDTQGDE Q9UP48/1-164 --------------------------------............---------------------------------------.-DKKLQLIKDYREKVESELRSIC.TTVLE.LLDKYLIANA..TNPESKVFYLKMKGDYFRYLAEVA.CGD.DRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYY..EILNNPELACTLAKTAF...DEAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDSAGEE 143T_HUMAN/3-236 KTELIQKAKLAEQAERYDDMATCMKAVTEQGA............ELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKTDT--.SDKKLQLIKDYREKVESELRSIC.TTVLE.LLDKYLIANA..TNPESKVFYLKMKGDYFRYLAEVA.CGD.DRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYY..EILNNPELACTLAKTAF...DEAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDSAGEE 143T_MOUSE/3-236 KTELIQKAKLAEQAERYDDMATCMKAVTEQGA............ELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKTDT--.SDKKLQLIKDYREKVESELRSIC.TTVLE.LLDKYLIANA..TNPESKVFYLKMKGDYFRYLAEVA.CGD.DRKQTIENSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYY..EILNNPELACTLAKTAF...DEAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDSAGEE Q9V5G6/6-144 KEELVQKAKLAEQSERYDDMAQAMKSVTETGV............ELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEA--.SARKQQLAREYRERVEKELREIC.YEVLEgLLDKYLIPKA..SNPESKVFYLKMKGDYYRYLAEVA.TGD.ARNS---------------------------------------..-----------------...----------..----..-------.------------------- 143Z_DROME/6-239 KEELVQKAKLAEQSERYDDMAQAMKSVTETGV............ELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEA--.SARKQQLAREYRERVEKELREIC.YEVLG.LLDKYLIPKA..SNPESKVFYLKMKGDYYRYLAEVA.TGD.ARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYY..EILNSPDKACQLAKQAF...DDAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDTQGDE 143G_BOVIN/3-240 REQLVQKARLAEQAERYDDMAAAMKNVTELNE............PLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADG.NEKKIEMVRAYREKIEKELEAVC.QDVLS.LLDNYLIKNCseTQIESKVFYLKMKGDYYRYLAEVA.TGE.KRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYY..EIQNAPEQACHLAKTAF...DDAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDQQDDD 143G_RAT/3-240 REQLVQKARLAEQAERYDDMAAAMKNVTELNE............PLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADG.NEKKIEMVRAYREKIEKELEAVC.QDVLS.LLDNYLIKNCseTQYESKVFYLKMKGDYYRYLAEVA.TGE.KRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYY..EIQNAPEQACHLAKTAF...DDAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDQQDDD Q9UDP2/1-212 --------------------------VTELNE............PLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADG.NEKKIEMVRAYREKIEKELEAVC.QDVLS.LLDNYLIKNCseTQYESKVFYLKMKGDYYRYLAEVA.TGE.KRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYY..EIQNAPEQACHLAKTAF...DDAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDQQDDD O70457/4-241 REQLVQKARLAEQAERYDDMAAAMKNVTELNE............PLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADG.NEKKIEMVRAYREKIEKELEAVC.QDVLS.LLDNYLIKNCseTQYESKVFYLKMKGDYYRYLAEVA.TGE.KRATVVESFEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYY..EIQNAPEQACHLAKTAF...DDAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDQQDDD 143G_HUMAN/4-238 -EQLVQKARLAEQAEGYDDMAAAMKNVTELNE............PLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADG.NE-KIEMVRAYREKVEKELEAVC.QDVLS.LVDNYLYKNCseTQYERKDLYLKMKGDYYRYLAEVA.TGE.KRGDVVESSEKAYSE-REISKEHMQPTHPIRLGLALNYSVFYY..EIQNAPEQACHLAKTEF...EDAIAELDTL..NEES..YKDSTLI.MQLLRDNLTLWTSDQQDDH Q28541/1-40 --------------------------------............---------------------------------------.-----------------------.-----.----------..------------------------.---.-------------------------------------------..-----------------...DDAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDQQDEE 143F_MOUSE/3-240 REQLLQRARLAEQAERYDDMASAMKAVTELNE............PLSNEDRNLLSVAYKNVVGARRSSWRVISSIEQKTMADG.NEKKLEKVKAYREKIEKELETVC.NDVLA.LLDKFLIKNCndFQYESKVFYLKMKGDYYRYLAEVA.SGE.KKNSVVEASEAAYKEAFEISKEHMQPTHPIRLGLALNFSVFYY..EIQNAPEQACLLAKQAF...DDAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDQQDEE 143F_HUMAN/3-240 REQLLQRARLAEQAERYDDMASAMKAVTELNE............PLSNEDRNLLSVAYKNVVGARRSSWRVISSIEQKTMADG.NEKKLEKVKAYREKIEKELETVC.NDVLS.LLDKFLIKNCndFQYESKVFYLKMKGDYYRYLAEVA.SGE.KKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFSVFYY..EIQNAPEQACLLAKQAF...DDAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDQQDEE 1433_CAEEL/5-237 VEELVQRAKLAEQAERYDDMAAAMKKVTEQGQ............ELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEG--.SEKKQQLAKEYRVKVEQELNDIC.QDVLK.LLDEFLIVKA..GAAESKAFYLKMKGDYYRYLAEVA.S-E.DRAAVVEKSQKAYQEALDIAKDKMQPTHPIRLGLALNFSVFYY..EILNTPEHACQLAKQAF...DDAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDVGAED O76466/1-54 --------------------------------............---------------------------------------.-----------------------.-----.----------..------------------------.---.-------------------------------------------..---NSPDKACQLAKQAF...DDAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDTAGDE 1434_CAEEL/5-238 KEELVNRAKLAEQAERYDDMAASMKKVTELGA............ELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEG--.SEKKQQMAKEYREKVEKELRDIC.QDVLN.LLDKFLIPKA..GAAESKVFYLKMKGDYYRYLAEVA.SGD.DRNSVVEKSQQSYQEAFDIAKDKMQPTHPIRLGLALNFSVFFY..EILNAPDKACQLAKQAF...DDAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDAATDD 1432_SCHMA/1-205 -----------------------------SNN............ELTNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEG--.SERKQQMAKDYREKIEKELKDIC.HEVLT.LLDKFLIPKA..TTAESKVFYLKMKGDYYRYLAEVA.TGD.ERQKVIEESQRAYNDAFDIAKNQMQPTHPIRLGLALNFSVFYY..EILNAPDRACHLAKQAF...DDAIAELDTL..NEDS..YKDSTLI.MQLLRDNLTLWTSDTGGDD O96945/8-241 -SPLTTKARIAEQAERYEDMAKFMKEVTEKAT...........eELSPDDRNLLSVAYKNVVGTRRSSWRVISSIEQKSSD--.-ENKKEMAKAYREKIEKELDEIC.NEVLT.LLDDHLLKKA..TSDESKVFYQKMKGDYYRYLAEVTpSGD.KREDVVVKAKDSYNKALEVATEKMPPTHPIRLGLALNFSVFHY..EIQNAPEKACEMAKKAF...DEAIAELDNL..KEDS..YKDSTLI.MQLLRDNLTLWTSEGQTEE O70456/3-238 RASLIQKAKLAEQAERYEDMAAFMKSAVEKGE............ELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEG.SEEKGPEVKEYREKVETELRGVC.DTVLG.LLDSHLIKGA..GDAESRVFYLKMKGDYYRYLAEVA.TGD.DKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHY..EIANSPEEAISLAKTTF...DEAMADLHTL..SEDS..YKDSTLI.MQLLRDNLTLWTADSAGEE O77642/3-238 RASLIQKAKLAEQAERYEDMAAFMKSAVEKGE............ELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEES.SEEKGPEVQEYREKVETELRGVC.DTVLG.LLDTHLIKEA..GDAESRVFYLKMKGDYYRYLAEVA.TGD.DKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHY..EIANSPEEAISLAKTTF...DEAMADLHTL..SEDS..YKDSTLI.MQLLRDNLTLWTADNAGEE 143S_HUMAN/3-238 RASLIQKAKLAEQAERYEDMAAFMKGAVEKGE............ELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEG.SEEKGPEVREYREKVETELQGVC.DTVLG.LLDSHLIKEA..GDAESRVFYLKMKGDYYRYLAEVA.TGD.DKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHY..EIANSPEEAISLAKTTF...DEAMADLHTL..SEDS..YKDSTLI.MQLLRDNLTLWTADNAGEE 1431_SCHMA/14-246 NTDLVHIAKLAEQAERYDDMAAAMKRYTEASG............NLGNEERNLLSVAYKNVVGARRSAWRVIHGSEMKAVN--.DRTKKQIAEEYRIKMEKELNTIC.NQVLA.LLEDYLLPNA..SPDDSKVFFLKMQGDYYRYLAEVA.TDD.ARTEVVQKSLDAYTKATTAA-ENLPTTHPIRLGLALNFSVFFY..EIQNDAAKACELAKSAF...DSAIAELDQL..QDDS..YKDSTLI.MQLLRDNLTLWASDQTAEG Q9U8K4/15-247 -SDLVQIAKLAEQAERYDDMAAAMKAYAELPA............ELGSEERNLFSVAYKNVVGARRSAWRVISAVEHKHDE--.NSKKRQLTKEYRVKMEEELNEIC.REVLT.LLSKYLTPKS..NGFESQVFYRKMEGDYYRFLAEVA.TGD.ARKEVVEKSQAAYEKATEIAEEMLPSTHPIRLGLALNFSMFYY..EIKCDPTQACNLAKRAF...DTSIGELDSL..QDDS..YKDSTLI.MQLLRDNLTLWASDQPEAE Q9SHV6/16-54 --------------------------------............---------------------------------------.-----------------------.-----.----------..------------------------.---.-------------------------------------------..-----------------...-EALMMLDAL..GDEL..YKDSTLI.MKILRDNLTFWTSDMTDEA Q24902/13-244 VDELVQRAKLAEQAERYDDMAGACKTMAEMGN............ELNNEERNLLSVAYKNVLGARRSSWRIMSSIAKKQAG--.-TPLADQTDIYLKKVEEELIPIC.NDVLA.-LPVLPITEK..IGAEAKIFYYKMMGDYYRYLAEVQ.EGE.QNDKSTEAAEEANQKATSLAEAELSVTHPIRLGLALNFSVFYY..EIKNMPEKACSLAKAAF...DAAITEVDSI..KDET..YKDSTLI.MQLLRDNLTLWNSECETDS Q9U408/13-244 VDELVQRAKLAEQAERYDDMAGACKTMAKMRN............ELNNEEANLLSVAYKNVVGARRSSWRIMSSIAKKQAG--.-TPLAHQHDIYLKKVEEELIQIC.NDVLA.-LPVLPITEK..IGAEAKIFYYKMMGDYYRYSAEVQ.EGE.QNDKSTEAAEEANQKATSLAEAELSVTHPIRLGLALNFSVFYY..EIKNMPEKACSLAKAAF...DAAITEVDSI..KDET..YKDSTLI.MQLLRDNLTLWNSECETDS 143L_ARATH/7-245 RDQYVYMAKLAEQAERYEEMVQFMEQLVTGATp.........aeELTVEERNLLSVAYKNVIGSLRAAWRIVSSIEQKEESRK.NDEHVSLVKDYRSKVESELSSVC.SGILK.LLDSHLIPSA..GASESKVFYLKMKGDYHRYMAEFK.SGD.ERKTAAEDTMLAYKAAQDIAAADMAPTHPIRLGLALNFSVFYY..EILNSSDKACNMAKQAF...EEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQEQM 143R_ARATH/7-245 RDQYVYMAKLAEQAERYEEMVQFMEQLVTGATp.........aeELTVEERNLLSVAYKNVIGSLRAAWRIVSSIEQKEESRK.NDEHVSLVKDYRSKVESELSSVC.SGILK.LLDSHLIPSA..GASESKVFYLKMKGDYHRYMAEFK.SGD.ERKTAAEDTMLAYKAAQDIAAADMAPTHPIRLGLALNFSVFYY..EILNSSDKACNMAKQAF...EEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDYAGAD 143K_ARATH/7-245 RDQYVYMAKLAEQAERYEEMVQFMEQLVSGATp.........agELTVEERNLLSGAYKNVIGSLRAAWRIVSSLEQKEESRK.NEEHVSLVKDYRSKVETELSSIF.SGILR.LLDSHLIPSA..TARESKVFYLKMKGDYHRYLAEFK.SGD.ERKTAAEDAMIAYKAAQDVAVADLAPTHPIRLGLALNFSVFYY..EILNSSEKACSMAKQAF...EEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQEQM Q9SWP7/7-245 RDQYVYMAKLAEQAERYEEMVQFMEQLVSGATp.........agELTVEERNLLSVAYKNVIGSLRAAWRIVSSIEQKEESRK.NEEHVSLVKDYRSKVETELSSIC.SGILR.LLDSHLIPSA..TASESKVFYLKMKGDYHRYLAEFK.SGD.ERKTAAEDTMIAYKAAQDVAVADLAPTHPIRLGLALNFSVFYY..EILNSSEKACSMAKQAF...EEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQEQM Q9SEC9/1-127 --------------------------------............---------------------------------------.-----------------------.-----.----------..GTRESKVFYLKMKGDYHRYMAEFK.VGD.ERKNAAEDTMNSYKAAQDIALADLAPTHPIRLGLALNFSVFYY..EILNSSDKACSMAKQAF...EEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDSQDQL 143B_SOYBN/6-244 REQYVYLANVSEQAERYEEMVEFMQKVVVGSTp.........asELTVEERNLLSVAYKNVIGSLRAAWRIVSSIEQKEEGRK.NDDHVSLVKHYRSKVENELTQVC.ATILS.LLDSNLVPSA..SASESKVFYLKMKGDYHRYLAEFK.VGD.ERKTATEDTMLSYKAAQDIASADLPPTHPIRLGLALNFSVFYY..EILNQSDKACAMAKQAF...EEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDVQDQL O24533/1-181 --------------------------------............-----------VAYKNVIGSLRAAWRIVSSIEQKEEGRK.NDDHVVLVKDYRSKVEAELSNVC.ASILE.LLDKNLIPSG..SSSESKVFYYKMKGDYHRYLAEFK.IGE.ERKSAAEDTMLSYKAAQDIAAADLPSTHPIRLGLALNFSVFYY..EILNQSDKACAMAKQAF...EEAIAELDTL..GEES..YKDSTLI.MQLFRDN------------ P93787/9-246 REQCLYLAKLAEQAERYEEMVKFMDKLVIGSGs..........sELTVEERNLLSVAYKNVIGSLRAAWRIVSSIEQKEEGRK.NDEHVVLVKDYRSKVESELSDVC.AGILK.ILDQYLIPSA..SAGESKVFYLKMKGDYYRYLAEFK.VGN.ERKEAAEDTMLAYKAAQDIAVAELAPTHPIRLGLALNFSVFYY..EILNASEKACSMAKQAF...EEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQEQM 1431_LYCES/9-246 REQCLYLANVAEQAERYEEMVKFMDKLVIGSGs..........sELTVEERNLLSVAYKNVIGSLRAAWRIVSSIEQKEEGRK.NDEHVVLVKDYRSKVESELSDVC.AGILK.ILDQYLIPSA..SAGESKVFYLKMKGDYYRYLAEFK.VGN.ERKEAAEDTMLAYKAAQDIAVADVAPTHPIRLGLALNFSVFYY..EILNASEKACSMAKQAF...EEAIAELDTM..GEES..YKDSTLI.MQLLRDNLTLWTSDMQEQM 143D_TOBAC/9-246 REQCLYLAKLAEQAERYEEMVKFMDRLVAVSAs..........sELTVEERNLLSVAYKNVIGSLRAAWRIVSSIEQKEEGRK.NEEHVVLVKDYRSKVESELSDVC.AGILK.ILDQYLIPSA..AAGESKVFYLKMKGDYYRYLAEFK.VGN.ERKEAAEDTMLAYKAAQDIALAELAPTHPIRLGLALNYSVFYY..EILNASEKACSMAKQAF...EEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQEQM Q9XEW6/1-118 ----------AEQAERYEEMVQFMQKLVIGNTp.........ggELNVEERNLLSVAYKNVIGSLRAAWRIVSSIEQKEEGRK.NEDHVVLVKEYRSKVESELSDIC.ASILR.LLDSNLIPSA..TASESKVFYLKMKGDY--------.---.-------------------------------------------..-----------------...----------..----..-------.------------------- Q9XEW3/1-100 ----------AEQAERYEEMVLFMQKLVLGNTp.........ggELNVEERNLLSVAYKNVIGSLRAAWRIVSSIEQKEEGRK.NEDHVVLVKEYRSKVESELSDVC.ASILR.LLDSNLVP--..------------------------.---.-------------------------------------------..-----------------...----------..----..-------.------------------- 143A_LYCES/11-138 REQCLYLAKLAEQAERYEEMVQFMDKLVLNSTp.........adDLTVEERNLLSVAYKNVIGSLRAAWRIVSSIEQKEESRK.NEEHVHLVKEYRGKVENELSQVC.AGILK.LLESNLVPSA..TTSESKVFHLKMKGDY--------.---.-------------------------------------------..-----------------...----------..----..-------.------------------- Q42020/1-90 --------------------------------............--------------------------------------G.NDDHVSLIRDYRSKIETELSDIC.DGILK.LLDTILVPAA..ASGDSKVFYLKMKGDYHRYLAEFK.SGQ.ERKDAAEHTLXAYKAAQDIANSEL-------------------..-----------------...----------..----..-------.------------------- 143C_ARATH/10-247 RDEFVYMAKLAEQAERYEEMVEFMEKVAKAVDk..........dELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NDDHVSLIRDYRSKIETELSDIC.DGILK.LLDTILVPAA..ASGDSKVFYLKMKGDYHRYLAEFK.SGQ.ERKDAAEHTLTAYKAAQDIANSELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWASDMQDDV Q9XEW7/1-93 ---DICRIXLAEQAERYEEMVEFMEKVTKGVEv..........eELTVEERNLLSVAYKNVIGARRASWRIIWSIEQKEESRG.NDEHVVTIREYRSKVESYLSACS.-----.----------..------------------------.---.-------------------------------------------..-----------------...----------..----..-------.------------------- Q9XEW8/1-86 ----------AEQAERYEEMVEFMEKVTKGVEv..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NDEHVVTIREYRSKVESYLSACS.-----.----------..------------------------.---.-------------------------------------------..-----------------...----------..----..-------.------------------- O49082/8-245 REENVYMAKLAEQAERYEEMVEFMEKVARTVDt..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVALIKDYRGKIEAELSKIC.DGILK.LLDSHLVPSS..TAAESKVFYLKMKGDYHRYLAEFK.SGA.ERKEAAESTLLAYKSAQDIALAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAISELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDINEEA Q9SP07/8-245 REENVYMAKLAEQAERYEEMVEFMEKVARTVDt..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVALIKDYRGKIEAELSKIC.DGILK.LLDSHLVPSS..TAPESKVFYLKMKGDYHRYLAEFK.SGA.ERKEAAESTLLAYKSAQDIALAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAISELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDINEEA O24222/3-240 REENVYMAKLAEQAERYEEMVEYMEKVAKTVDv..........eELTVEERNLLSVAYKNVIGARRASWRIVSSIEQKEEGRG.NEEHVTLIKEYRGKIEAELSKIC.DGILK.LLDSHLVPSS..TAAESKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTMVAYKAAQDIALADLAPTHPIRLGLALNFSVFYY..EILNSPDKACNLAKQAF...DEAISELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDLTEDG 1432_MAIZE/8-245 REENVYMAKLAEQAERYEEMVEFMEKVAKTVDs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEEGRG.NEDRVTLIKDYRGKIETELTKIC.DGILK.LLESHLVPSS..TAPESKVFYLKMKGDYYRYLAEFK.TGA.ERKDAAENTMVAYKAAQDIALAELAPTHPIRLGLALNFSVFYY..EILNSPDRACSLAKQAF...DEAISELDTL..SEES..YKDSTLI.MQLLHDNLTLWTSDISEDP 1431_MAIZE/8-245 REENVYMAKLAEQAERYEEMVEFMEKVAKTVDs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEEGRG.NEDRVTLIKDYRGKIETELTKIC.DGILK.LLETHLVPSS..TAPESKVFYLKMKGDYYRYLAEFK.TGA.ERKDAAENTMVAYKAAQDIALAELAPTHPIRLGLALNFSVFYY..EILNSPDRACSLAKQAF...DEAISELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDISEDP O24221/9-246 REENVYMAKLAEQAERYEEMVEFMEKVAKTVDs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDRVTLIKDYRGKIETELTKIC.DGILK.LLESHLVPSS..TAPESKVFYLKMKGDYYRYLAEFK.TGA.ERKDAAENTMVAYKAAQDIALAELPPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAISELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDISEDT O24001/9-246 REENVYMAKLAEQAERYEEMVEFMEKVAKTVDs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDRVTLIKEYRGKIETELSKIC.DGILK.LLETHLVPSS..TAPESKVFYLKMKGDYYRYLAEFK.SGP.ERKDAAENTMVAYKAAQDIALAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAISELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDITEDT 143B_HORVU/9-246 REENVYMAKLAEQAERYEEMVEFMEKVAKTVDs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDRVTLIKDYRGKIEVELTKIC.DGILK.LLDSHLVPSS..TAPESKVFYLKMKGDYYRYLAEFK.SGT.ERKDAAENTMVAYKAAQEIALAELPPTHPIRLGLALNFSVFYY..EILNSPDRACDLAKQAF...DEAISELDSL..SEES..YKDSTLI.MQLLRDNLTLWTSDISEDA 143P_ARATH/4-241 REENVYMAKLAEQAERYEEMVEFMEKVAKTVDv..........eELSVEERNLLSVAYKNVIGARRASWRIISSIEQKEESKG.NEDHVAIIKDYRGEIESELSKIC.DGILN.VLEAHLIPSA..SPAESKVFYLKMKGDYHRYLAEFK.AGA.ERKEAAESTLVAYKSASDIATAELAPTHPIRLGLALNFSVFYY..EILNSPDRACSLAKQAF...DDAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMTDEA Q42053/5-100 REENVYMAKLAEQAERYEEMVEFMEKVAKTVDv..........eELSVEERNLLSVAYKNVIGARRASWRIISSIEQKEESKG.NEDHVAIIKDYRGKIESELSKIC.-----.----------..------------------------.---.-------------------------------------------..-----------------...----------..----..-------.------------------- 1433_ORYSA/8-245 REENVYMAKLAEQAERYEEMVEFMEKVAKTTDv..........gELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEAYVASIKEYRSRIETELSKIC.DGILK.LLDSHLVPSA..TAAESNVFYLKMKGDYHRYLAEFK.SGA.ERKEAAENTLVAYKSAQDIALADLPTTHPIRLGLALNLSVFYY..EILNSPDRACNLAKQAF...DDAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDNAEDG 143A_HORVU/8-245 REENVYMAKLAEQAERYEEMVEFMEKVAKTADv..........gELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEAYVASIKEYRTRIETELSKIC.DGILK.LLDSHLVPSA..TAAESKVFYLKMKGDYHRYLAEFK.AGA.ERKEAAENTLVAYKSAQDIALADLPTTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDSL..GEES..YKDSTLI.MQLLRDNLTLWTSDNAEEG 1434_LYCES/6-243 REENVYLAKLAEQAERYEEMIEFMEKVAKTADv..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVNTIKEYRSKIEADLSKIC.DGILS.LLESNLIPSA..STAESKVFHLKMKGDYHRYLAEFK.TGT.ERKEAAENTLLAYKSAQDIALAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAISELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDNADDV 1433_SOLTU/5-242 REENVYMAKLAEQAERYEEMVEFMEKVAKVDV...........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVSSIKEYRVKIEAELSKIC.DGILS.LLESHLVPSA..STAESKVFYLKMKGDYHRYLAEFK.TGArERKEAAENTLLAYKSAQDIALAELTPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DDAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDTTDDA 143E_TOBAC/6-243 REENVYMAKLAEQAERYEEMVEFMEKVAKTVDv..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVSSIKEYRGKIEAELSKIC.DGILN.LLESHLIPVA..STAESKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAENTLLAYKSAQDIALAELAPTHPIRLGLALNFSVFYY..EILNSSDRACNLAKQAF...DDAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDTTVSL 1433_MESCR/7-244 REENVYMAKLAEQAERYEEMVEFMEKVAKMTDt..........eELSVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVSTIKEYRGKIETELSKIC.DGILN.LLESHLIPSA..STAESKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAENTLLAYKSAQDIALAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAISELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDNAEEG 143U_ARATH/7-244 REENVYLAKLAEQAERYEEMVEFMEKVAKTVEt..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEDSRG.NSDHVSIIKDYRGKIETELSKIC.DGILN.LLEAHLIPAA..SLAESKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLVAYKSAQDIALADLAPTHPIRLGLALNFSVFYY..EILNSSDRACSLAKQAF...DEAISELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDLNDEA 143N_ARATH/5-242 REENVYLAKLAEQAERYEEMVEFMEKVAKTVDt..........dELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NDDHVSIIKDYRGKIETELSKIC.DGILN.LLDSHLVPTA..SLAESKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLVAYKSAQDIALADLAPTHPIRLGLALNFSVFYY..EILNSPDRACSLAKQAF...DEAISELDTL..GEES..YKDSTLI.MQLLRDNLTLWNSDINDEA O81976/1-54 --------------------------------............---------------------------------------.-----------------------.-----.----------..------------------------.---.-------------------------------------------..---NSSDRACNLAKQAF...DEAISELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDITDDA 143A_SOYBN/6-243 REENVYMAKLADEAERYEEMVEFMEKVAKTVEv..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVAIIKEYRGKIEAELSKIC.DGILN.LLESNLIPSA..ASPESKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLLAYKSAQDIALADLAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAISELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDITDIA 1435_LYCES/5-242 REENVYMANVADEAERYEEMVEFMEKVVAALNg..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVASIKKYRSQIENELTSIC.NGILK.LLDSKLIGSA..ATGDSKVFYLKMKGDYYRYLAEFK.TGT.ERKEAAENTLSAYKSAQDIANGELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDDG 1434_SOLTU/5-241 REENVYMANVAARAERYEEMVEFMEKVVAALD...........tELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVASIKKYRSQIENELTSIC.NGILK.LLDSKLIGSA..ATGDSKVFYLKMKGDYYRYLAEFK.TGT.ERKEAAENTLSAYKSAQDIANGELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIADVDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDDG 1435_SOLTU/5-243 REENVYMAKLAEQAERYEEMVEFMEKVVAAADg.........aeELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVASIKEYRSKIESELTSIC.NGILK.LLDSKLIGSA..ATGDSKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAENTLSAYKAAQDIANAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDDG 1436_LYCES/5-243 REENVYMANVAEQRRSYEEMVEFMEKVVAAADg.........aeELTVEERILLSVAYKNVMGARRASWRIISSIEQKEESRG.NEDHVASIKEYRSKIESELTSIC.NGILK.LLDSKLIGSA..ATGDSKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAENTLSAYKAAQDIANAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTSWTSDMQDDG 143A_TOBAC/5-241 REENVYLAKLAEQAERYEEMVEFMEKVVGAGD...........dELTIEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVASIKTYRSKIESELTSIC.NGILK.LLDSKLIGTA..ATGDSKVFYLKMKGDYYRYLAEFK.TGA.ERKEAAENTLSAYKSAQDIANGELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELGTL..GEES..YKDSTLI.MQLFCDNLTLWTSDMQDDG 143F_TOBAC/5-243 RDEFVYMAKLAEQAERYEEMVDFMEKVVTAADg.........geELTIEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVTSIKTYRSKIESELTSIC.NGILK.LLDSNLIRAA..STGDSKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAENTLSSYKSAQDIANAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDEG 1433_HELAN/8-246 REENVYLAKLAEQAERYEEMVEFMEKVVAAADg.........geELTIEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEGHVSTIRDYRSKIESELSSIC.DGILK.VLDSKLIGSA..SGGDSKVFYLKMKGDYYRYLAEFK.TGD.ERKLAAENTLSAYKAAQDIANAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEDS..YKDSTLI.MQLLRDNLTLWTSDMQDDT 1433_LYCES/9-246 REENVYMAKLADRAESDEEMVEFMEKVSNSLGs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEEHVNSIREYRSKIENELSKIC.DGILK.LLDSKLIPSA..TSGDSKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLTAYKAAQDIASAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDDG Q9SCA7/1-230 --ENVYMAKLADRAESDEEMVEFMEKVSNSLGs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEEHVNSIREYRSKIENELSKIC.DGILK.LLDSKLIPSA..TSGDSKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLTAYKAAQDIASAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTS------ P93786/8-245 REENVYMAKLAEQAERYEEMVEFMEKVSNSLGs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEEHVNSIREYRSKIENELSKIC.DGILK.LLDSKLIPSA..TSGDSKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLTAYKAAQDIASAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDDG 143C_TOBAC/8-245 REENVYMAKLAEQAERYEEMVEFMEKVSNSLGs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEEHVNSIREYRSKIENELSKIC.DGILK.LLDAKLIPSA..ASGDSKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDDG Q42260/1-75 --------------------------------............---------------------------------------.-----------------------.-----.----------..------------------------.---.-------------------------PTHPIRLGLALNSSVFYY..EILNSPDRGCNLAKQGF...DEAIAELDTL..GEES..NKDSTLI.MQLLRDNLTLWTSDMQDDV P93785/3-240 REENVYMAKLAEQAERYEEMVQFMEKVSTSLGs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEEHVKCIKEYRSKIESELSNIC.DGILK.LLDSNLIPSA..SNGDSKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLSAYKAAQDIANTELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDDG 1432_LYCES/3-240 REENVYMANVAEQAERYEEMVQFMEKVSTSLGs..........eELTVEERNLLSVAYKNVIGARTLAWRIISSIEQKEESRG.NEEHVKCIKEYRSKIESELSDIC.DGILK.LLDSNLIPSA..SNGDSKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLSAYKAAQDIANTELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDDG 143B_TOBAC/3-241 REENVYMAKLAEQAERYEEMVSFMEKVSTSLGt.........seELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVKCIQEYRSKIESELSNIC.DGILK.LLDSCLIPSA..SAGDSKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLSAYKAAQDIANAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDDG Q9T0N0/8-245 REENVYMAKLAEQAERYEEMVEFMEKVSANADs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVDVIRDYRSKIESELSNIC.DGILK.LLDTRLIPSA..SSGDSKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLAAYKSAQDIANAELPPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDDG 1433_PEA/8-245 REENVYMAKLAEQAERYEEMVEFMEKVSANADs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVAVIRDYRSKIESELSNIC.DGILK.LLDTRLIPSA..SSGDSKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLTGYKSAQDIANAELPPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDDG 1433_OENHO/8-245 REENVYLAKLAEQAERYEEMVEFMEKVCAAADs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NDDHVSTIRDYRSKIETELSNIC.GGILK.LLDSRLIPSA..ASGDSKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLSAYKAAQDIANAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLANEAF...DEAIAELDTL..EEES..YKDSTLI.MQLLRDNLTLWTSDMQDDG Q9XG89/8-245 REEFVYMAKLAEQAERYEEMVEFMEKVTAAVEs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NDEHVTVIRDYRSKIETELSNIC.NGILK.LLDSRLIPSA..ALGDSKVFYLKMKGDYHRYLAEFK.SGA.ERKDAAESTLTAYKSAQDIANTELPPTHPIRLGLALNFSVFYY..EILNSPDRACGLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDDG 143A_VICFA/8-245 REEFVYMAKLAEQAERYEEMVEFMEKVTAAVEs..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NDEHVSVIRDYRSKIETELSNIC.NGILK.LLDSRLIPSA..ALGDSKVFYLKMKGDYHRYLAEFK.SGA.ERKDAAESTLTAYKSAQDIANTELPPTHPIRLGLALNFSVFYY..EILNSPDRACGLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDDG Q39558/8-246 REEFVYLAKLAEQAERYEEMVEFMEKVSAAVDn..........eELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NDDHVSIIRDYRSKIETELSNICgFRILN.LLDSRLIPSA..ASGDSKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLTAYKSAQDIANAELPPTHPIRLGLALNFSVFYY..EILNSPDRACSLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDIRGSR 143O_ARATH/5-242 REELVYMAKLAEQAERYEEMVEFMEKVSAAVDg..........dELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NDDHVTAIREYRSKIETELSGIC.DGILK.LLDSRLIPAA..ASGDSKVFYLKMKGDYHRYLAEFK.TGQ.ERKDAAEHTLAAYKSAQDIANAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDDA 143H_ARATH/11-248 REEFVYLAKLAEQAERYEEMVEFMEKVAEAVDk..........dELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRG.NDDHVTTIRDYRSKIESELSKIC.DGILK.LLDTRLVPAS..ANGDSKVFYLKMKGDYHRYLAEFK.TGQ.ERKDAAEHTLTAYKAAQDIANAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAIAELDTL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDES Q42083/11-79 REEFVYLAKLAAEAERYEEMVEFMEKVAEAVDk..........dELTVEERNLLSVAYKNVIGARRASWRIISSIEQKK----.-----------------------.-----.----------..------------------------.---.-------------------------------------------..-----------------...----------..----..-------.------------------- 1433_SPIOL/1-198 --------------------------------............------RNLLSVAYKNVVGARRASWRIISSIEQKEESRG.NEDHVSVIRDYRSRIEKELSDNC.DGILK.LLDTKLVPAA..SSGDSKVFYLKMKGDYHRYLAEFK.TGA.QRKEAAESTLTAYKAAQDIANAELAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...VEAIAELDTL..GEDS..YKDSTLI.MQLLRDNLTLWTSDMQDEA 143X_MAIZE/1-56 --------------------------------............---------------------------------------.-----------------------.-----.----------..------------------------.---.-------------------------------------------..-ILNSPDRACNLAKQAF...DEAISELDSL..GEES..YKDSTLI.MQLLXDNLTLWTSDTNEDG O24223/8-249 REESVYKAKLAEQAERYEEMVEYMERVARAAGgas......ggeELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEEGRG.NDAHAATIRSYRGKIEAELARIC.DGILA.LLDSHLVPSA..GAAESKVFYLKMKGDYHRYLAEFK.SGD.ERKQAAESTMNAYKAAQDIALADLAPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKQAF...DEAISELDSL..GEES..YKDSTLI.MQLLRDNLTLWTSDANDDG Q42106/1-38 --------------------------------............---------------------------------------.-----------------------.-----.----------..------------------------.---.-------------------------------------------..-----------------...--AIXELDTL..NEES..YKDSTLI.MQLLRDNLTLWTSDISEEG Q9XEW4/21-220 -----------------------------ENE............ELTVEERNFLSVAYKNVIGARRASWRIISSIEQKEESRG.NEDHVSVIRDYRAKIETELSSIC.DGILK.LLDSRLIPTA..SAGDPKVFYLKMKGDYHRYLAEFK.TGA.ERKEAAESTLTAYKAAQDIANAELAPTHPIRXGLALNFSVFYY..EILNSPDRACSLAKQAF...DEAISELDTL..GEES..YKDSTLI.MQLLRDNLTLWT------- 1433_CHLRE/5-242 REECVYMAKLAEQAERYDEMVEEMKKVAKLVHd..........qELSVEERNLLSVAYKNVIGARRASWRIISSIEQKEEAKG.NEEHVQRIRKYRTVVEEELSKIC.ASILQ.LLDDHLIPTA..STGESKVFYLKMKGDYHRYLAEFK.TGA.DRKEAAEHTLLAYKAAQDIALVDLPPTHPIRLGLALNFSVFYY..EILNSPERACHLAKQAF...DEAIAELDSL..GEES..YKDSTLI.MQLLRDNLTLWTSDMQDPA Q9VEA8/4-239 RENNVYKAKLAEQAERYDEMVEAMKKVASMDV............ELTVEERNLLSVAYKNVIGARRASWRIITSIEQKEENKG.AEEKLEMIKTYRGQVEKELRDIC.SDILN.VLEKHLIPCA..TSGESKVFYYKMKGDYHRYLAEFA.TGS.DRKDAAENSLIAYKAASDIAMNDLPPTHPIRLGLALNFSVFYY..EILNSPDRACRLAKAAF...DDAIAELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDMQAED 143E_DROME/4-239 RENNVYKAKLAEQAERYDEMVEAMKKVASMDV............ELTVEERNLLSVAYKNVIGARRASWRIITSIEQKEENKG.AEEKLEMIKTYRGQVEKELRDIC.SDILN.VLEKHLIPCA..TSGESKVFYYKMKGDYHRYLAEFA.TGS.DRKDAAENSLIAYKAASDIAMNDLPPTHPIRLGLALNFSVFYY..EILNSPDRACRLAKAAF...DDAIAELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDMQAED O57468/4-239 REDLVYRAKLAEQAERYDEMVESMKKVAGMDV............ELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKG.GEDKLKMIREYRQMVETELKSIC.NDILD.VLDKHLIPAA..SSGESKVFYYKMKGDYHRYLAEFA.QGN.DRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYY..EILNSPDRACRLAKAAF...DDAIAELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDMQGDG 143E_HUMAN/4-239 REDLVYQAKLAEQAERYDEMVESMKKVAGMDV............ELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKG.GEDKLKMIREYRQMVETELKLIC.CDILD.VLDKHLIPAA..NTGESKVFYYKMKGDYHRYLAEFA.TGN.DRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYY..EILNSPDRACRLAKAAF...DDAIAELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDMQGDG 1433_DICDI/3-238 REENVYMAKLAEQAERYEEMVETMKKVAELDV............ELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESKG.NENHVKKIKEYKCKVEKELTDIC.NDILE.VLESHLIVSS..ASGESKVFYYKMKGDYFRYLAEFA.TGN.PRKTSAESSLIAYKAASDIAVTELPPTHPIRLGLALNFSVFYY..EILNSPDRACNLAKTAF...DDAIAELDTL..SEDS..YKDSTLI.MQLLRDNLTLWTSDVHNME 1433_CANAL/5-240 REDSVYLAKLAEQAERYEEMVENMKAVASSGQ............ELSVEERNLLSVAYKNVIGARRASWRIVSSIEQKEEAKG.NESQVALIRDYRAKIEAELSKIC.EDILS.VLSDHLITSA..QTGESKVFYYKMKGDYHRYLAEFA.IAV.FRKEAADLSLEAYKAASDVAVTELPPTHPIRLGLALNFSVFYY..EILNSPDRACHLAKQAF...DDAVADLETL..SEDS..YKDSTLI.MQLLRDNLTLWTDLSEAPA Q9UR29/5-240 REDSVYLAKLAEQAERYEEMVENMKRVASSDQ............ELTVEERNLLSVAYKNVIGARRASWRIVSSIEQKEESKG.NEAQVSMIKGYREKIETELAEIC.EDILD.VLDKHLIPSA..ASGESKVFYHKMMGDYHRYLAEFA.TGD.KRKESADKSLEAYKAASDVAVTELPPTHPIRLGLALNFSVFYY..EILNSPDRACHLAKQAF...DDAIAELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDMQDSA 1433_TRIHA/3-238 HEDAVYLAKLAEQAERYEEMVENMKIVASEDR............DLTVEERNLLSVAYKNVIGARRASWRIVTSIEQKEESKG.NSSQVTLIKEYRQKIENELAKIC.DDILE.VLDQHLIPSA..KSGESKVFYHKIKGDYHRYLAEFA.IGD.RRKDSADKSLEAYKAATEVAQTELPPTHPIRLGLALNFSVFYY..EILNAPDQACHLAKQAF...DDAIAELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSSEAETP BMH1_YEAST/4-240 REDSVYLAKLAEQAERYEEMVENMKTVASSGQ............ELSVEERNLLSVAYKNVIGARRASWRIVSSIEQKEESKEkSEHQVELICSYRSKIETELTKIS.DDILS.VLDSHLIPSA..TTGESKVFYYKMKGDYHRYLAEFS.SGD.AREKATNASLEAYKTASEIATTELPPTHPIRLGLALNFSVFYY..EIQNSPDKACHLAKQAF...DDAIAELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDMSESG Q06854/1-144 --------------------------------............---------------------------------------.---------------------IS.DDILS.VLDSHLIPSA..TTGESKVFYYKMKGDYHRYLAEFS.SGD.AREKATNASLEAYKTASEIATTELPPTHPIRLGLALNFSVFYY..EIQNSPDKACHLRKQAF...DDAIAELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDMSESG BMH2_YEAST/4-240 REDSVYLAKLAEQAERYEEMVENMKAVASSGQ............ELSVEERNLLSVAYKNVIGARRASWRIVSSIEQKEESKEkSEHQVELIRSYRSKIETELTKIS.DDILS.VLDSHLIPSA..TTGESKVFYYKMKGDYHRYLAEFS.SGD.AREKATNSSLEAYKTASEIATTELPPTHPIRLGLALNFSVFYY..EIQNSPDKACHLAKQAF...DDAIAELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDISESG RA25_SCHPO/5-240 RENSVYLAKLAEQAERYEEMVENMKKVACSND............KLSVEERNLLSVAYKNIIGARRASWRIISSIEQKEESRG.NTRQAALIKEYRKKIEDELSDIC.HDVLS.VLEKHLIPAA..TTGESKVFYYKMKGDYYRYLAEFT.VGE.VCKEAADSSLEAYKAASDIAVAELPPTDPMRLGLALNFSVFYY..EILDSPESACHLAKQVF...DEAISELDSL..SEES..YKDSTLI.MQLLRDNLTLWTSDAEYNQ RA24_SCHPO/6-241 REDAVYLAKLAEQAERYEGMVENMKSVASTDQ............ELTVEERNLLSVAYKNVIGARRASWRIVSSIEQKEESKG.NTAQVELIKEYRQKIEQELDTIC.QDILT.VLEKHLIPNA..ASAESKVFYYKMKGDYYRYLAEFA.VGE.KRQHSADQSLEGYKAASEIATAELAPTHPIRLGLALNFSVFYY..EILNSPDRACYLAKQAF...DEAISELDSL..SEES..YKDSTLI.MQLLRDNLTLWTSDAEYSA 1433_FUCVE/4-237 RDDLVYMAKLAEQAERFDEMVDHMKAVAQQPK............ELSVEERNLLSVAYKNVIGSRRASWRVISSIEGKDTV--.-SDQLPLIRDYKSKIETELTDIC.ADILK.IIEAELIPNS..TSEEGKVFYYKMKGDYHRYLAEFQ.SAD.ERKTSASDALDAYQLASDHANQDLPPTHPIRLGLALNFSVFYY..EILNSPDRACGLAKAAF...DDAIAELDTL..SEES..YKDSTLIiMQLLRDNLTLWTSDQGEAE 1433_TOBAC/5-239 REKQVYLARLAEQAERYDEMVEAMKTVAKMDV............ELTVEERNLVSVGYKNVIGARRASWRILSSIEQKEESKG.HDQNVKRIKTYQQRVEDELTKYA.LT-LS.VIDEHVVPSS..TSGESTVFYYKMKGDYYRYLAEFK.SGD.DRKEAADQSLKAYEAATATASADLAPTHPIRLGLALNFSVFYY..EILNSPERACHLAKQAF...DEAIAELDSL..SEES..YKDSTLI.MQLLRDNFTLWTSDLEEGG 1437_LYCES/5-129 REKQVYLARLAEQAHTYDEMVEAMKAIAKMDV............ELTVEERNLVSVGYNNVIGATRASWRILSSIEQKEESKG.HEQNVKRIKTYRQRVEDELTKYA.AYILS.VIDELLVPSS..TTGESIVFYYKMKGDY--------.---.-------------------------------------------..-----------------...----------..----..-------.------------------- Q9S9Z8/5-240 RAKQVYLAKLNEQAERYDEMVEAMKKVAALDV............ELTIEERNLLSVGYKNVIGARRASWRILSSIEQKEESKG.NEQNAKRIKDYRTKVEEELSKIC.YDILA.VIDKHLVPFA..TSGESTVFYYKMKGDYFRYLAEFK.SGA.DREEAADLSLKAYEAATSSASTELSTTHPIRLGLALNFSVFYY..EILNSPERACHLAKRAF...DEAIAELDSL..NEDS..YKDSTLI.MQLLRDNLTLWTSDLEEGG 143E_ARATH/5-240 REKQVYLAKLSEQTERYDEMVEAMKKVAQLDV............ELTVEERNLVSVGYKNVIGARRASWRILSSIEQKEESKG.NDENVKRLKNYRKRVEDELAKVC.NDILS.VIDKHLIPSS..NAVESTVFFYKMKGDYYRYLAEFS.SGA.ERKEAADQSLEAYKAAVAAAENGLAPTHPVRLGLALNFSVFYY..EILNSPESACQLAKQAF...DDAIAELDSL..NEES..YKDSTLI.MQLLRDNLTLWTSDLNEEG 1438_LYCES/7-131 RESLVYIARLAEQRERYDEMVDAMKNVANLDV............ELTVEERNLLSVGYKNVVGSRRASWRILSSIEQKEDASG.NEQNVKRIQGYRQKVESELTDIC.NNIMT.VIDEHLIPSC..TAGESTVFYYKMKGDY--------.---.-------------------------------------------..-----------------...----------..----..-------.------------------- 1439_LYCES/7-131 RENFVYVAKLAEQAERYDEMVEAMKNVANMDV............ELTVEERNLLSVGYKNVVGSRRASWRILSSIEQKEESRG.NEQNVKRIKEYLQKVESELTNIC.NDIMV.VIDQHLIPSC..SAGESTVFYHKMKGDY--------.---.-------------------------------------------..-----------------...----------..----..-------.------------------- 143C_SOYBN/7-242 RENFVYVAKLAEQAERYEEMVEAMKNVANLNV............ELTVEERNLLSVGYKNVVGARRASWRILSSIEQKEEAKG.NDVSVKRIKEYRLKVESELSNIC.SDIMT.VIDEYLIPSS..SSGEPSVFFYKMKGDYYRYLAEFK.SGD.ERKEAADHSMKAYQLASTTAEAELASTHPIRLGLALNFSVFYY..EILNSPERACHLAKQAF...DEAISELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDIPEDG 143B_VICFA/7-242 RENFVYIAKLAEQAERYEEMVDSMKNVANLDV............ELTIEERNLLSVGYKNVIGARRASWRILSSIEQKEESKG.NDVNAKRIKEYRHKVETELSNIC.IDVMR.VIDEHLIPSA..AAGESTVFYYKMKGDYYRYLAEFK.TGN.EKKEAGDQSMKAYESATTAAEAELPPTHPIRLGLALNFSVFYY..EILNSPERACHLAKQAF...DEAISELDTL..NEES..YKDSTLI.MQLLRDNLTLWTSDIPEDG O49152/7-242 RETFVYVAKLAEQAERYEEMVDSMKNVATLDV............ELTVEERNLLSVGYKNVIGARRASWRILSSIEQKEEAKG.NEVNAKRIKEYRQKVESELTNIC.NDVMR.VIDEHLIPSA..SAGESTVFYYKMKGDYYRYLAEFK.TGN.EKKEAGDQSMKAYESATAAAEAELPPTHPIRLGLALNFSVFYY..EILNSPERACHLAKQAF...DEAISELDTL..NEES..YKDSTLI.MQLLRDNLTLWTSDIPEDG 143D_SOYBN/7-242 RENFVYIAKLAEQAERYEEMVESMKNVANLDV............ELTVEERNLLSVGYKNVIGARRASWRILSSIEQKEETKG.NELNAKRIKEYRQKVELELSNIC.NDVMR.VIDEHLIPSA..AAGESTVFYYKMKGDYYRYLAEFK.SGN.EKKEAADQSMKAYESATAAAEADLPPTHPIRLGLALNFSVFYY..EILNSPERACHLAKQAF...DEAISELDTL..NEES..YKDSTLI.MQLLRDNLTLWTSDIPEDG Q9XEW5/1-219 ----------AEQAERYDEMVDAMKKVAKLDV............ELTVEERNLLSVGYKNVIGARRASWRILSSIEQKEESKG.NETNVKRIKEYRKKVEAELTGVC.NDIMT.VIDEHLIPSS..IPGESAVFYYKMKGDYYRYLAEFK.SGN.ERKEAADQSLKAYETATSTAARDLSPTHPIRLGLALNFSVFYY..EIMNSPERACHLAKQSF...DEAISELDTL..SEES..YKDSTLI.MPLLKDNLTLWT------- O80367/7-242 RDTFVYLAKLSEQAERYEEMVESMKSVAKLNV............DLTVEERNLLSVGYKNVIGSRRASWRIFSSIEQKEAVKG.NDVNVKRIKEYMEKVELELSNIC.IDIMS.VLDEHLIPSA..SEGESTVFFNKMKGDYYRYLAEFK.SGN.ERKEAADQSLKAYEIATTAAEAKLPPTHPIRLGLALNFSVFYY..EIMNAPERACHLAKQAF...DEAISELDTL..NEES..YKDSTLI.MQLLRDNLTLWTSDISEEG 143M_ARATH/7-242 RDTFVYLAKLSEQAERYEEMVESMKSVAKLNV............DLTVEERNLLSVGYKNVIGSRRASWRIFSSIEQKEAVKG.NDVNVKRIKEYMEKVELELSNIC.IDIMS.VLDEHLIPSA..SEGESTVFFNKMKGDYYRYLAEFK.SGN.ERKEAADQSLKAYEIATTAAEAKLPPTHPIRLGLALNFSVFYY..EIMNAPERACHLAKQAF...DEAISELDTL..SEES..YKDSTLI.MQLLRDNLTLWTSDISEEG Q42058/7-112 RDTFVYLAKLSEXAERYEEMVESMKSVAKLNV............DLTVEERNLLSVGYKNVIGSRRASWRIFSSIEQKEAVKG.NDXNVKRIKEYMEKVELELSNIC.IDIMS.VLDEHLI---..------------------------.---.-------------------------------------------..-----------------...----------..----..-------.------------------- 1433_ENTHI/1-236 SEDCVFLSKLAEQSERYDEMVQYMKQVAALNT............ELSVEERNLLSVAYKNVIGSRRASWRIITSLEQKEQAKG.NDKHVEIIKGYRAKIEDELAKYC.DDVLK.VIKENLLPNA..STSESKVFYKKMEGDYYRYYAEFT.VDE.KRQEVADKSLAAYTEATEISNADLAPTHPIRLGLALNFSVFYY..EIMNDADKACQLAKQAF...DDSIAKLDEV..PESS..YKDSTLI.MQLLRDNLTLWTSDTADEE 1431_ENTHI/4-239 REDCVYTAKLAEQSERYDEMVQCMKQVAEMEA............ELSIEERNLLSVAYKNVIGAKRASWRIISSLEQKEQAKG.NDKHVEIIKGYRAKIEKELSTCC.DDVLK.VIQENLLPKA..STSESKVFFKKMEGDYYRYFAEFT.VDE.KRKEVADKSLAAYTEATEISNAELAPTHPIRLGLALNFSVFYF..EIMNDADKACQLAKQAF...DDAIAKLDEV..PENM..YKDSTLI.MQLLRDNLTLWTSDACDEE 1432_ENTHI/4-238 REDLVYLSKLAEQSERYEEMVQYMKQVAEMGT............ELSVEERNLISVAYKNVVGSRRASWRIISSLEQKEQAKG.NTQRVELIKTYRAKIEQELSQKC.DDVLK.IITEFLLKNS..TSIESKVFFKKMEGDYYRYYAEFT.VDE.KRKEVADKSLAAYQEATDTA-ASLVPTHPIRLGLALNFSVFYY..QIMNDADKACQLAKEAF...DEAIQKLDEV..PEES..YKESTLI.MQLLRDNLTLWTSDMGDDE Q9UAH0/5-239 REELIYMAKIAEQTERFEDMLEYMKKVVQTGQ............ELSVEERNLLSVAYKNTVGSRRSAWRSISAIQQKEESKG.S-KHLDLLTNQKKKIETELNLYC.DDILK.LLNDFLIKNA..TNAEAQVFFLKMKGDYYRYIAEYA.QGD.EHKKAADGALDSYNKACEIANSELRPTHPIRLGLALNFSVFHY..EVLNDPSKACTLAKTAF...DEAIGDIERI..QEDQ..YKDATTI.MQLIRDNLTLWTSEFQDDA Q9XYW8/1-233 -----YLAMLAEQCSRYKEMVQFLEDMVKQRD...........kDLNSDERNLLSIAYKNSISGGRSAVRTIMAYEAKEKKKE.NSTFLPYITEYKKQVEDELTKLC.QGVLK.TTDEQLLKKA..EDDEAKVFYIKMKGDYNRYIAEYA.EGD.LKKQVSDDALKAYDEATEIA-KTLPVLNPIALGLALNFSVFYY..EVINDHKKAIEIAKAAV...EKADKELPNI..DEDAdeNRDTVSI.YNLLKENLDMWVSEEEGDQ O61173/2-194 -EKNVYLAMLAEQCSRYKEMVQFLEDMVKQRD...........kDLNSDERNLLSIAYKNSISGGRSAVRTIMAYEAKEKKKE.NSTFLPYITEYKKQVEDELTKLC.QGVLK.TTDEQLLKKA..EDDEAKVFYIKMKGDYNRYIAEYA.EGD.LKKQVSDDALKAYDEATEIA-KTLPVLNPIALGLALNFSVFYY..EVINDHKKAIEIAKA--...----------..----..-------.------------------- Q9XYW7/4-229 -EKQVYLAMLAEQCSRYEDMMTFLEDMVKAKA...........eDLSSDERNLLSIAYKNTISLDRQAIRTLLAYESKEAKKA.ESPYLDYIKEYKAKVQKELEDLC.NKINR.TIDDNLLPKA..TTDEAKVFYHKMKGDYCRYIAENV.DGD.TKKKYSDEGLAAYNAALEAA-KNIDYKNPVKLGLALNLSVFYY..EVVGNKDEACKLAEDTLsksKEALNGADE-..EEDE..VKDAMSI.VNLLEENL----------- Q9SFK4/1-214 -----------------------MRKVCELDI............ELSEEERDLLTTGYKNVMEAKRVSLRVISSIEKMEDSKG.NDQNVKLIKGQQEMVKYEFFNVC.NDILS.LIDSHLIPST.tTNVESIVLFNRVKGDYFRYMAEFG.SDA.ERKENADNSLDAYKVAMEMAENSLAPTNMVRLGLALNFSIFNY..EIHKSIESACKLVKKAY...DEAITELDGL..DKNI..CEESMYI.IEMLKYNLSTWTSGDGNGN Q9XZV0/2-235 KEELLNRCKLNDLIENYGEMFEYLKELSHIKI............DLQPDELDLITRCTKCYIGHKRGQYRKILTLIDKDKIVD.NQKNSALLEILRKKLSEEILLLC.NSTIE.LSQNFLNNNV..FPKKTQLFFTKIIADHYRYIYEIN.GKE.DIKLKAKEYYE--KGLQTIKTCKYNSTETAYLTFYLNYSVFLH..DTMRNTEESIKVSKACL...YEALKDTEDI..VDNS..QKDIVLL.CQMLKDNISLWKTETNEDN #=GC SS_cons HHHHHHHHHHHHHTTCHHHHHHHHHHHHTTSC............CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTT--.CCHHHHHHHHHHHHHHHHHHHHH.HHHHH.HHHHTTTTCC..CSCHHHHHHHHHHHHHHHHHHHHC.CSC.HHHHHHHHHHHHHHHHHHHHHCHCCTTCHCHHHHHHHHHHHHC..HTSCCHHHCHHHHHHHH...HHHHTTCGGC..CTTT..HHHHHHH.HHHHHHHHHHCTCCCXXXX #=GC SA_cons 26310320300350512510050022003352............4045500400120033002310402420152179179--.38752510440144014203510.43002.0035201642..754403000010100011100201.867.7465125302500340252067635113122100001001127..31372485135106412...5415867932..3994..6651462.142043126627759XXXX //