SIGNATURE Applications

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The SIGNATURE programs were developed by Jon Ison and colleagues at MRC HGMP for their protein domain research. They are included as an EMBASSY package as a work in progress.

Applications in the current signature release

Program name	Description
libgen	Generate discriminating elements from alignments
matgen3d	Generate a 3D-1D scoring matrix from CCF files
rocon	Generates a hits file from comparing two DHF files
rocplot	Performs ROC analysis on hits files
siggen	Generates a sparse protein signature from an alignment
siggenlig	Generate ligand-binding signatures from a CON file
sigscan	Generate hits (DHF file) from a signature search
sigscanlig	Search ligand-signature library & write hits (LHF file)

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